Computational Systems Biology

Computational Systems Biology

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The recent confluence of high throughput methodology for biological data gathering, genome-scale sequencing, and computational processing power has driven a reinvention and expansion of the way we identify, infer, model, and store relationships between molecules, pathways, and cells in living organisms. In Computational Systems Biology, expert investigators contribute chapters which bring together biological data and computational and/or mathematical models of the data to aid researchers striving to create a system that provides both predictive and mechanistic information for a model organism. The volume is organized into five major sections involving network components, network inference, network dynamics, function and evolutionary system biology, and computational infrastructure for systems biology. As a volume of the highly successful Methods in Molecular Biologya„c series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.Comprehensive and up-to-date, Computational Systems Biology serves to motivate and inspire all those who wish to develop a complete description of a biological system.Speed of Response The network diagram allows calculation of the average path length between nodes in the full network or in any subgraph. ... as a plug-in to Cytoscape (85), which is an open source network visualization and analysis tool.


Title:Computational Systems Biology
Author: Jason McDermott
Publisher:Humana PressInc - 2009-04-01
ISBN-13:

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